Pakistan reopened the border crossing with Iran in the western town of Taftan on Saturday.
Trucks were allowed to cross the border after a 14-day quarantine imposed over fears of coronavirus spillover from Iran, the Geo News channel said.
Hundreds of trucks loaded with liquefied petroleum were stranded in Pakistan after it closed the border last month, following first reports of infection with the COVID-19 viral disease in Iran.
The number of confirmed cases in Iran has spiked by over 1,000 to 5,823 since Friday. A health ministry spokesman said 21 more people died from the disease in the past day, bringing the death toll to 145.